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2019

November 22, 2019
Background: Rehospitalization due to suicidal ideation (SI) or suicidal attempt (SA) could be used to measure effectiveness of depression treatments in patients at risk for suicide. There is limited…
November 22, 2019
Introduction: Lumateperone (ITI-007) is in development for the treatment of schizophrenia and bipolar depression. Lumateperone has a unique mechanism of action that simultaneously modulates serotonin…
November 22, 2019
Introduction: RBP-7000 (PERSERIS™) is a once-monthly, subcutaneous, extended-release risperidone formulation that is approved for treating schizophrenia in adults and is designed to deliver…
November 22, 2019
Objective: Determine if AMPH EROS has an onset of effect at 30 minutes post-dose in children with ADHD.
November 22, 2019
Using the same DSM-5 diagnostic criteria for Borderline Personality Disorder (BPD) as in adults, but only requiring a 1 year duration, adolescents as young as 13, with a pattern of immature…
November 22, 2019
Background: Antipsychotic treatment has been linked to hyperprolactinemia, which can lead to increased nonadherence and changes in sexual hormones in both men and women. Here, we evaluated the…
November 22, 2019
In adults with attention-deficit/hyperactivity disorder (ADHD), reductions in ADHD-Rating Scale-IV total score (ADHD-RS-IV-TS) were significantly greater with SHP465 mixed amphetamine salts (MAS)…
November 22, 2019
Objective: Evaluate efficacy and safety of a 2-month dose of aripiprazole lauroxil (AL) with a 1-day initiation regimen during hospitalization for an acute exacerbation of schizophrenia.
November 22, 2019
Background: Studies examining treatment responses to antidepressants based on genotype have produced inconsistent findings. Although catechol-O-methyltransferase (COMT) metabolizes catecholamines,…
November 22, 2019
Introduction: Lumateperone (ITI-007) is in late-phase clinical development for schizophrenia. Lumateperone has a unique mechanism of action that modulates serotonin, dopamine, and glutamate…
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